Edwin G. Krebs

Explore the timeline of Edwin G. Krebs, a pioneering biochemist and Nobel Prize winner, detailing his significant contributions to the field of enzymology, key milestones in his career, and his impactful legacy in medical research.

Born: June 06, 1918
Biochemist

6 juni 1918

1 september 1936

15 januari 1943

1 januari 1953

1 januari 1968

1 januari 1988

10 december 1992

1 juni 2001

21 december 2009

06juni
1918
06 June 1918

Birth of Edwin G. Krebs

Edwin Gerhard Krebs was born on June 6, 1918, in Lansing, Iowa, USA. He was one of the four children of William Carl Krebs and Louise Helen Stegeman. His early years were influenced by the financial struggles of the Great Depression, and he developed a strong work ethic during his formative years. His father was a Presbyterian minister which also influenced his upbringing.

01september
1936
01 September 1936

Enrollment at University of Illinois

In September 1936, Edwin G. Krebs enrolled at the University of Illinois at Urbana-Champaign. He was initially interested in chemistry, influenced by his high school experiences, and later shifted his focus to biochemistry. This period laid the foundation for his future career in science and research, leading him to pursue advanced studies.

15januari
1943
15 January 1943

Graduation from Washington University School of Medicine

Edwin G. Krebs graduated from Washington University School of Medicine in St. Louis with an M.D. degree on January 15, 1943. During his time there, he was attracted to basic research, which steered him toward a career that combined medical training with a passion for biochemical research. This educational achievement was a pivotal point in his career.

01januari
1953
01 January 1953

Co-discovery of Protein Phosphorylation

In 1953, Edwin G. Krebs, along with Edmond H. Fischer, discovered reversible protein phosphorylation. This groundbreaking discovery showed that the addition of a phosphate group to a protein can regulate its function, which is a fundamental mechanism for cellular processes. This work had a profound impact on biochemistry and cell biology, shaping the future of molecular biology research.

01januari
1968
01 January 1968

Appointment at University of Washington

In 1968, Edwin G. Krebs accepted a position as Chair of the Department of Pharmacology at the University of Washington School of Medicine. Under his leadership, the department grew in prominence and contributed significantly to the fields of pharmacology and biochemistry. His role as chair reflected his influence and reputation in the scientific community.

01januari
1988
01 January 1988

Retirement from Active Faculty

Edwin G. Krebs retired from the active faculty at the University of Washington in 1988. After retirement, he continued to contribute to the scientific community through advisory roles and remained an influential figure in scientific circles. His career left a lasting legacy on the field of biochemistry and pharmacology.

10december
1992
10 December 1992

Awarded Nobel Prize in Physiology or Medicine

On December 10, 1992, Edwin G. Krebs, along with Edmond H. Fischer, was awarded the Nobel Prize in Physiology or Medicine for their discoveries concerning reversible protein phosphorylation. Their work unveiled the regulatory role of reversible protein phosphorylation and its significance in cells, providing a universal mechanism for biochemical regulation. This recognition was one of the most prestigious acknowledgments of their scientific contributions.

01juni
2001
01 June 2001

Publication of Autobiography

In June 2001, Edwin G. Krebs published an autobiography recounting his journey through scientific endeavours and personal experiences. This work provided insights into his early life, scientific curiosity, and the process leading to his groundbreaking research. The autobiography is a reflective piece that offers a comprehensive view of his life and career.

21december
2009
21 December 2009

Death of Edwin G. Krebs

Edwin G. Krebs passed away on December 21, 2009, in Seattle, Washington, at the age of 91. His contributions to biochemistry, particularly the discovery of reversible protein phosphorylation, have left a lasting impact on scientific research. He is remembered as a pioneering scientist and a revered figure in the scientific community.

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