FC Twente announced a multi-year collaboration with the University of Twente on July 1, 2020. This partnership aimed to foster innovation and development in sports science and management, benefiting both institutions and enhancing the club's professional infrastructure.

On April 16, 2018, FC Twente appointed Marino Pusic as their new head coach, tasked with leading the team through a challenging period following their relegation from the Eredivisie. Pusic's appointment was part of the club's efforts to stabilize and return to the top flight of Dutch football.

After being relegated in 2017, FC Twente achieved immediate promotion back to the Eredivisie on April 2, 2018, showcasing their resilience and determination to return to top-tier football. Their successful campaign in the Eerste Divisie was a testament to their efforts to reclaim their position in Dutch football.

After several difficult seasons and financial troubles, FC Twente was relegated from the Eredivisie on May 31, 2017. This was a significant setback for the club, which had enjoyed previous success in Dutch football. The relegation marked the beginning of a rebuilding process for Twente.

The Grolsch Veste stadium, home to FC Twente, underwent significant expansion and renovation, which was completed on April 21, 2014. This development increased the stadium's capacity to over 30,000, making it one of the larger football stadiums in the Netherlands and enhancing the matchday experience for fans.

By winning the Eredivisie in the 2009-2010 season, FC Twente qualified for the UEFA Champions League group stage for the first time in their history. This milestone was achieved on May 2, 2010, and it marked the club's entry into Europe's premier club competition, showcasing their progress on a continental level.

FC Twente won their first Eredivisie title in the 2009-2010 season under the management of Steve McClaren. The title was secured on April 2, 2010, with a 2-0 victory over NAC Breda. This triumph marked a historic achievement as it was the club's first national championship.

FC Twente secured their first KNVB Cup victory on May 24, 2001, after defeating PSV Eindhoven in a dramatic match that concluded with a penalty shoot-out. This victory represented a significant achievement for the club and qualified them for UEFA Cup competition the following season.

De Grolsch Veste stadium was officially inaugurated on May 10, 1998, marking the beginning of a new era for FC Twente. With modern facilities and a larger capacity, the stadium became the new home of the club and played an integral role in their future successes.

Diekman Stadion, the former home of FC Twente, officially opened on September 14, 1977. The stadium served as the club's home ground for many years before the team moved to their current stadium, De Grolsch Veste. It played a significant role in the club's history until its closing in 1998.

In the 1973-74 season, FC Twente had a remarkable run in the UEFA Cup, reaching the final. They faced Borussia Mönchengladbach in the final, held over two legs. Despite a spirited performance, Twente lost 5-1 on aggregate, but the achievement marked a high point for the club in European competition.

FC Twente was founded on July 1, 1965, as a result of the merger between two clubs, Enschedese Boys and Sportclub Enschede. The club was established to create a stronger football presence in the city of Enschede, Netherlands. Over the years, FC Twente has developed a strong fanbase and has become one of the leading clubs in Dutch football.