In 2019, the University of Southern California completed the construction of Michelson Hall, a cutting-edge facility devoted to research and innovation in convergent biosciences. The hall hosts collaborative research efforts in areas such as engineering, life sciences, and chemistry, fostering interdisciplinary approaches to solving complex global challenges.

The USC Annenberg School for Communication and Journalism established the Annenberg Media Center in 2016 to serve as a hub for student journalism. The center provides state-of-the-art facilities for students to engage in digital and broadcast journalism, supporting USC's commitment to training the next generation of media professionals in an evolving communication landscape.

In 2011, legendary filmmaker George Lucas made a historic gift of $1 billion to the University of Southern California, marking one of the largest donations in the university's history. The gift supported the institution's endowment and ensured continued excellence in its programs, particularly benefiting the School of Cinematic Arts, which Lucas himself attended.

The USC Stevens Institute for Innovation was established in 2006 to promote innovation and entrepreneurship at USC. By providing resources, mentorship, and support for USC students and faculty, the institute aims to transform ideas into market-ready products and services, fostering a culture of creativity and innovation across disciplines.

Founded in 2001, the Brain and Creativity Institute at USC is dedicated to investigating the connections between neural systems, creativity, and human experience. By using advanced neuroimaging techniques, the institute explores the neural basis of emotions, arts, and decision-making, contributing significantly to the scientific understanding of the brain.

The USC Rossier School of Education underwent significant reforms in 1994 aimed at revolutionizing educational practices and policies. These reforms included a focus on urban education, equity, and diversity, and led the school to become a leader in educational research and reform initiatives, impacting public education throughout California and the United States.

The Department of Computer Science at the University of Southern California was established in 1965. As one of the earliest departments in the United States dedicated to computer science, it has been at the forefront of research and education in computing. The department has contributed significantly to fields such as artificial intelligence, virtual reality, and computer vision.

In 1928, the University of Southern California opened the Viterbi School of Engineering. Named after Andrew Viterbi in recognition of his accomplishments and support, the school has become a leading institution in engineering education and research. It offers numerous undergraduate and graduate programs that contribute to technological advancements and innovation worldwide.

The University of Southern California established its School of Cinematic Arts in 1904, making it one of the oldest and most prestigious film schools in the world. The school was instrumental in the development of the cinematic arts in Hollywood, offering programs that cover a wide range of media disciplines, including film and television production, screenwriting, and new media.

The University of Southern California (USC) was founded on October 6, 1880, in Los Angeles, California. It was established by a group of public-spirited citizens with a mission to create an institution reflective of both the opportunities and challenges of its region. USC was the first private research university in California and has grown to become a leading institution in various fields, offering undergraduate, graduate, and professional degrees.