In 2020, Myrthe Hilkens published a significant investigative report on the influence of media on public opinion. The report examined how media narratives shape societal perceptions and the role of journalism in maintaining an informed citizenry, highlighting her commitment to media literacy.

In 2018, Myrthe Hilkens launched a podcast series that delves into pressing social issues, offering a platform for diverse voices and expert opinions. The series has been praised for its insightful analysis and ability to engage listeners in meaningful conversations about contemporary challenges.

In 2015, Myrthe Hilkens joined NRC, one of the leading newspapers in the Netherlands, as a journalist. At NRC, she has been involved in writing in-depth articles and opinion pieces, focusing on societal issues, media, and culture, contributing to the paper's reputation for quality journalism.

After serving in the Dutch House of Representatives, Myrthe Hilkens returned to journalism in September 2013. She resumed her career with a renewed focus on investigative journalism, leveraging her political experience to provide deeper insights into social and political issues.

Myrthe Hilkens was elected as a Member of the Dutch House of Representatives for the Labour Party (PvdA) in June 2011. During her tenure, she focused on issues such as media policy, youth, and social affairs, bringing her journalistic insights into the political arena.

In 2008, Myrthe Hilkens published her influential book 'McSex: de pornoficatie van de samenleving', which explores the impact of pornography on society. The book sparked widespread debate in the Netherlands about the normalization of sexual imagery and its effects on culture and relationships.