In 2022, Astrid Kersseboom hosted a special program on climate change, highlighting the urgent issues facing the Netherlands and the world. Her ability to present complex scientific data in an accessible manner was praised, further cementing her reputation as a versatile and skilled journalist.

During the COVID-19 pandemic, Astrid Kersseboom was at the forefront of NOS's coverage, providing critical updates and information to the public. Her reporting during this period was crucial in keeping the nation informed about the evolving situation and government responses.

Astrid Kersseboom has been a key reporter on matters concerning the Dutch Royal Family. In 2018, her coverage of royal events and issues surrounding the monarchy showcased her versatility as a journalist, adept at covering both political and cultural topics with equal skill.

In 2015, Astrid Kersseboom conducted a high-profile interview with Dutch Prime Minister Mark Rutte. The interview was noted for its depth and the challenging questions posed, reflecting Kersseboom's commitment to journalistic integrity and her ability to engage with top political figures.

Astrid Kersseboom played a significant role in covering the Dutch general elections in 2012. Her reporting provided insightful analysis and comprehensive coverage of the political landscape, helping viewers understand the implications of the election results.

In 2004, Astrid Kersseboom took on the role of news anchor for NOS Journaal. This position elevated her profile significantly, as she became one of the main faces delivering the news to the Dutch public. Her calm demeanor and professionalism have been widely appreciated by viewers.

Astrid Kersseboom began her career at NOS Journaal in 1990, marking the start of a long and distinguished tenure with the Dutch public broadcaster. Her role at NOS has seen her evolve from a reporter to a prominent news anchor, becoming a trusted face in Dutch journalism.